top of page

Lee Wong

Professor Lee Wong, Monash University

Dr Wong specialises in telomeres, which are complexes found at the ends of chromosomes that are essential for maintaining chromosome stability. Each time a cell divides, telomeres become shorter and when the cells have gone through many divisions the telomeres become so short that the cells die. This is a protective mechanism against cancer because mutations can accumulate after many cell divisions. However, in some cancer cells, the telomeres do not shorten because an enzyme called telomerase is expressed at higher-than-normal levels or because a series of molecular events called "Alternative Lengthening of Telomeres (ALT) is turned on. This ALT pathway is common in brain tumours. Most children with DIPG express a mutation that is associated with the ALT pathway. This study investigated the link between this mutation in a Histone 3.3 gene and switching on the ALT pathway.

Associate Professor

Misty Jenkins,

WEHI

Dr Ryan Duchatel,

University of Newcastle

Dr Jason Cain,

Hudson institute

for Medical Research

Dr Pouya Faridi,

Monash University

Professor
Peter Rogers,
University of Melbourne

Associate Professor Jeffrey Mann,
Monash University

Other research grant recipients

Contact Us

Email:

info@isabella

andmarcus

foundation.org

Khush De Rose:

0434 430 035

Daniela Ruberto:

0412 339 673

For media enquiries:

Robert De Rose:

0422 625 913

Address

4 Stephen Rd,

Dandenong South,

Victoria 3175

Follow Us

The Isabella and Marcus Foundation

@isabellamarcusfoundation

Isabella and Marcus Foundation

© 2024 by Isabella and Marcus Foundation

Contact Us

Email:

info@isabellaandmarcusfoundation.org

Khush De Rose: 0434 430 035

Daniela Ruberto: 0412 339 673

For media enquiries:

Robert De Rose: 0422 625 913

Address

4 Stephen Rd,

Dandenong South,

Victoria 3175

Follow Us

The Isabella and Marcus Foundation

@isabellamarcusfoundation

Isabella and Marcus Foundation

© 2024 by Isabella and Marcus Foundation

bottom of page